Could This Antibiotic Have Caused Your Tendonitis?

What is the connection between Cipro and Tendonitis? You might be shocked to find out that your antibiotic might be the cause of your tendonitis. However, tendonitis is not the only problem these drugs can cause; Cipro, along with the other Fluoroquinolone class of antibiotics, such as Levaquin and Avelox, can also lead to other serious problems. With tens of thousands of reports of disability and even death, these are not antibiotics that you want to mess with unnecessarily. If you are unfamiliar with this class of antibiotics, you can read the Introduction to Fluoroquinolone Antibiotics here.
Despite the reports of tendonitis, Achilles Tendon Rupture, and even life-threatening health problems, One Half of All Antibiotic Use is Unnecessary, and they are prescribed improperly up to 96% of the time in specific cases, such as in Chronic Sinus Infections and Bladder Infections. So, not only might you have tendonitis from taking that antibiotic, unless you were given the antibiotic for a life-threatening infection you might not have even needed the antibiotic in the first place!
Connective Tissue Destruction
While there is much debate about how much damage these drugs do, there is no debate that Cipro and tendonitis are related, and that this class of drugs even leads to tendon rupture. In fact, the FDA even has a Black Box Warning, the strongest warning possible for a drug, about the risk of tendon rupture with these drugs, and one study claims, “Tendinopathy are classic side effects observed with fluoroquinolones antibiotics” 1. Studies show that the risk of tendon rupture is double2 or triple 3 in those who take Fluoroquinolone antibiotics. In people over 60 who are also taking corticosteroids such as prednisone, the risk increases up to 6 times 4!
A newer study sought to look at whether these drugs damage other types of connective tissue, and found that Fluoroquinolones also damage the connective tissue of joints, leading to Arthritis from Fluoroquinolones. They also damage the connective tissue of the arteries, leading to a Doubling of the Risk of Aortic Aneurysm, a serious and even deadly condition where the largest artery in the body is damaged.
Common Sense Tells You that Cipro and Tendonitis are Related
Since it’s even known HOW Fluoroquinolones destroy collagen and connective tissue 5 6, including causing DNA Damage and Mitochondrial Disorder to the tendon cells, it simply makes sense that they can cause less damage to tendons than a tendon rupture, that leads to painful conditions such as tendonitis and tendonopathy. Cipro and Levaquin and tendonitis obviously are related, and are a serious problem for those experiencing this painful condition.
However, the risk of tendonitis is less recognized and understood by doctors, even to the point of denial by most doctors. It’s a well-known problem in the scientific literature, that’s been reported thousands of times, but doctors simply fail to recognize it in the vast majority of cases. This may be because a tendon rupture is easily diagnosed using ‘objective’ measurements that cannot be debated. In other words, a doctor can do a test where a tendon rupture can actually be seen, and where other doctors would be able to look at the same test and agree that a tendon rupture occurred.
“The sudden onset of some tendinopathies,
occasionally after a single dose of a fluoroquinolone,
suggests a direct toxic effect on collagen fibres.”
Fluoroquinolones and risk of Achilles tendon disorders: case-control study
Tendonitis, however, is almost never able to be actually seen on tests, and its diagnosis most often relies on people’s reports of pain. This makes tendonitis less able to be reliably diagnosed by doctors because there is no ‘objective’ measurement of tendonitis. In many cases, doctors won’t even BELIEVE people with reports of Cipro and tendonitis, despite extensive literature supporting the fact that Fluoroquinolones absolutely can and do lead to tendonitis, tendinopathy, and tendon rupture.
What Not to Do
If you have experienced problems with Cipro and tendonitis or Levaquin and tendonitis, what can you do? First of all, you have to understand the problem that caused your tendonitis. Fluoroquinolone antibiotic tendonitis is not ‘ordinary’ tendonitis caused from inflammation and overuse like the kind that people get from working on computers all day. Fluoroquinolone tendonitis is caused by a vicious cycle of the antibiotics reacting with your unique set of underlying health problems and genetic quirks.
The ‘standard’ doctors’ advice of rest and anti-inflammatory drugs is not only unlikely to be effective, but it’s likely to make things drastically worse. You see, the Fluoroquinolone Drug Interactions, such as taking steroidal anti-inflammatory drugs like Prednisone and Levaquin together, or even just taking Ibuprofen and a Fluoroquinolone together makes it MORE likely that you’ll rupture a tendon, and so is certainly not the remedy for tendonitis.
Treating with steroidal or non-steroidal anti-inflammatory drugs are exactly the WRONG remedy for tendonitis, since these drugs should be avoided like the plague when tendonitis was caused by Fluoroquinolones 7. It might be considered medical malpractice if a doctor treats Fluoroquinolone tendonitis with either a steroidal or non-steroidal anti-inflammatory drug!
This fact is absolutely well-known to the scientists who study these drugs, and yet it’s extraordinarily common for doctors to prescribe this time-bomb of inappropriate drugs together, both while you are taking the antibiotics and when you complain of tendonitis from Fluoroquinolones. It’s a lose-lose situation that your doctor and pharmacist are likely to ignorantly perpetrate against you if you don’t do your own research.
The Best Thing You Can Do
If you are experiencing the problem of Cipro and tendonitis, then you absolutely MUST build your body up and resolve the underlying health problems that allowed you to experience the problems you are now experiencing. The only way that we know for you to do this is to get and follow the protocol in The Fluoroquinolone Toxicity Solution. The staff here at FQ Research do the work we do because we were damaged by the Fluoroquinolones, just like you have been.
We used the Fluoroquinolone Toxicity Solution and got the largest amount of recovery from the protocol than from anything else we tried. It’s a tried and true protocol that makes good common sense, resolves your underlying health problems, and gives you a path to wellness. Get the book and follow the protocol. It’s guaranteed that you won’t regret it, which is another reason we recommend it.
- In Vitro Discrimination of Fluoroquinolones Toxicity on Tendon Cells Involvement of Oxidative Stress ↩
- Fluoroquinolones and collagen associated severe adverse events ↩
- use of fluroquinolones and risk of achilles tendon rupture ↩
- Fluoroquinolones and risk of Achilles tendon disorders: case-control study ↩
- Fluoroquinolone-associated Tendinopathy ↩
- Fluoroquinolones cause changes in extracellular matrix, signalling proteins, metalloproteinases and caspase-3 in cultured human tendon cells ↩
- Evidence of Tendinitis Provoked by Fluoroquinolone Treatment ↩
Temporary Whole-Body Tendinitis After Kidney Probe – Twice!
Ted Cloak, December 2016
I’m a healthy 85-year-old male.
Seven years ago, a urologist gave me Cipro to prevent infection while probing for a kidney stone. A few days later, my whole body gradually tightened up until I could not move without severe pain. Then the condition gradually went away, leaving no apparent trace. The episode lasted about five days, as I recall, peaking during day 3. There’s no question that Cipro was the culprit and tendinitis the condition.
Last August, I underwent a colonic resection to remove a cancerous tumor. There was no sign of tendinitis. I’m not sure what antibiotics were involved, if any, but I can find out.
Last month, November 2016, I had another probe for a kidney stone. I understand that Bactrim was the preventive antibiotic used, and that it is not in the same family as Cipro. Again, I went through a five-day period of increasing and decreasing whole-body tendinitis even worse, I think, than the earlier one. At its peak, I could not even turn over in bed (for once, I appreciated having a Foley catheter installed). Even my jaws were affected.
The recent episode began, and ended, with calf pain while walking; not sure about the 2009 episode in that regard. I now have no symptoms of tendinitis, and no apparent aftereffects. I’m getting out and walking, and plan to restart my regimen at the gym, gradually of course, next week. Oh, I do have a dysfunctional right posterior tibial tendon which developed a year or two ago; custom-made orthotics helps a lot. I don’t think it’s related.
OK, my questions: Has anyone else experienced this reaction to an antibiotic? Is there any literature that might help to explain it? What metabolic pathway(s) are involved between antibiotic and tendinitis?
I have a hunch: Perhaps the extra-strong drug seriously impacts some part of the intestinal flora that produces some essential element in the lubricant of the tendon sheath. That, if true, would explain (1) the history of the episodes — time delay, gradual onset, gradual recovery, and (2) how two very different drugs could have very similar/identical effect — as antibiotics, they are just doing their job, only too well.
Hi Ted,
This article explains that tens of thousands of others have experienced tendonitis from the Fluoroquinolones, and many articles on this site and the studies we link to explain the many mechanisms.
When i was approx 64 years of age I had an ear infection sufficiently severe to warrant a trip to the doctors who prescribed ciprofloxacin. The medicine packaging did not have a leaflet inside. I took one tablet per day for 3 days and then had a tremendous pain in both heels . I decided to get some info on the medicine and found that it caused rupture of the Achilles tendons in men over 60 and particularly men who had taken Testosterone prescribed by another doctor years before.
The doctor who originally prescribed Ciprofloxacin said he was sorry he prescribed that drug. I then read that Ciprofloxacin had been black boxed by the US FDA.
Up to the time of that episode i was a fairly healthy individual but in the years following I have developed many health problems too many to mention here.
I am a healthy 76 year old male. Last month I was prescribed a two week course of ciprofloxacin antibiotic after two courses of moxacillin and one other antibiotic for an ear infection probably caused be having my ears syringed, one week later I awoke with severe pain in both ankles I was advised to use anti inflammatory gel and pain killers. I am still in pain two weeks later and have been advised it could take months to recover. Having read your information regarding this drug ciprofloxacin I would have refused it and requested an alternative. What are my options now regarding a cure for tendonitis in my heels.
I had a reaction about 10 years ago after being on ciprofloxin for 3days . The tenon in my right calf was so se ere I was afraid to take a step. Recovery was slow and I actually had other weird health issues after. Like acute breast bone pain where I had to do little puffs to breathe and was ambulanced to hospital. Also taking a bike ride suddenly no strength at all in my ankle like it was amputated. I might add that being asthmatic has had me on prednisone for years.
Just recently I took cipro for a chest infection and my hips and rt knee has such pain aometimes I am afraid to move into a wlkimosition. I am a 70yr old female and wonder how to rebound. I had chiropractic and deep tissue massage and for a bit i thought I was paralyzed. If an antibiotic can cause such issues why is it still being sold.
I took one does of Cipro, 500 mg in September of 2016 and within hours I was in agony, unable to put any weight on my right leg. I needed a cane for three days just to get around and it took a week for the pain to fully go away. I took amoxicillin last month and after two days of taking it with no problems, on the 3rd day, the exact same pain returned to my right leg. I was unable to walk for 3 days without a cane. My doctor’s office (now ex-doctor) refused to see me and told me over the phone that it was not possible for amoxicillin to cause such a reaction. I am terrified to take any antibiotic and I can’t even find a doctor who cares or believes me. It is extremely frustrating.
Sharon, I had a similar reaction to the Cipra more than 3 months ago. I was given it for a UTI, and the next morning I woke with a burning pain in my left inner ankle. I had not read the side effects earlier ( a mistake I won’t make again) and after reading them, found, among several others, severe burning pain in ankle tendons. I threw away the rest of the Cipra, also tossed several other meds with disturbing side effects. Maybe not the best idea, but not taking any chances. Still have periodic bouts of ankle burning, once or twice a week, lasting about 1/2 hr. Just dealing with them.
I am a 55 year old women. The doctor gave me Cipro 500 mg x day to treat a bad UTI. About the 9th day in of taking the medication, my right knee started to bother me going up and down the stairs. That was a week ago and now both of my knees are hurting. I have a DR appt tomorrow and never usually turn to the web for advice, but after reading all these stories and the side effects of Cipro, and how Drs don’t believe Cipro can cause this type of pain in tendons, I really don’t know what to do!!
I am wondering if it’s possible to develop Cipro induced tendonitis more than 2 years after taking it? I was on IV and oral for infection and surgery. But, about 3 months ago I was aware of pain in the tendon running across my right shin and could barley walk for more than 2….certainly not without pain. I am at a loss as to what else could have caused this sudden onset? My ankles hurt and I feel as though I have weakened structural support…if that makes sense. Thank you
Yes, absolutely. Remember, the damage is cumulative, and the damage from running is cumulative. So the 2 together can cause damage years later. HOWEVER, pain does not mean that you have damage. Pain can just be pain. Damage usually causes pain, but all pain is not necessarily from damage.
This is happening to me right now. My achilles have ruptured and it hurts to walk. My doctor says its ok for me to take Meloxicam but it seems to have made it worse. What do I do?
I am 64. I took Cipro for 7 days for a UTI recently. At this time about a week later both of my knees are bothering me and both of them are swollen one more than the other. I know that it is the Cipro because I am an avid cyclist and I don’t have trouble in these areas.